| Can An Apple And A Daisy's Stem Cells
Teach Your Skin To Be Young Again? Dear Reader: If you bit into an Uttwiler Spatlauber apple, you probably wouldn't like it. It's not tasty. Its sourness would make your lips pucker. In fact, these trees were almost forgotten. There are only 20 left on the entire planet.1 But if you make an anti-aging stem cell serum from these apples, the results are nothing short of an instant facelift. These apples can do something unique... Something any woman who has tried to erase the wrinkles time leaves on her face would be envious of... These apples can heal themselves quickly and thoroughly. Cut into them... And the apple will swiftly form a new protective layer of skin. In winter storage, they outlast all other fruits, staying firm and smooth when other apples wrinkle and shrivel.2,3 Now, I've traveled around the world, uncovering nutritional treasures... I've pioneered formulas that change your cells' age at the genetic level... When this anti-aging stem cell cream from an apple and a daisy reach the skin cells on your face, they dramatically reduce their age at the genetic level. This triggers remarkable facelifting transformations where you tighten sagging skin, reduce wrinkles, erase the fine lines around your eyes, and restore a more youthful complexion. This remarkable discovery started when Swiss scientists managed to extract the stem cells from these apples and a resilient daisy. Because these scientists didn't settle for just concentrating this vital apple's juice... They didn't just hope for the best by plopping it into a skin cream... They went a step further... They figured out how to isolate and extract stem cells - special "signal molecules" that trigger this apple's healing ability. With amazing results. We're entering into a whole new chapter in natural skin care. With this new skin care breakthrough, We Can Now Transfer That Apple's Wisdom To Your Body Because of this extraordinary power, when the Uttwiler Spatlauber apple extract became public, the whole world of elite anti-aging skincare went into a frenzy. I'll admit, I'm not the only anti-aging expert to jump on it... Michelle Obama wrote a letter about it... Jennifer Lopez swears by it...Vogue ran a full page article on it...Savvy, beauty-conscious women worldwide are singing its praises.4,5 But there's one problem... Most Celebrity Skin Care Formulas Didn't Go Far Enough! | Meet Al Sears, M.D.
America's #1 Anti-Aging MD Pioneers Natural Beauty
In An Unnatural World  As one of the first doctors ever to be board certified in anti-aging medicine and a certified nutritionist, Dr. Al Sear, MD, specializes in developing natural beauty formulas to help his patients avoid the synthetic, toxic chemicals used in today's unnatural products. Pure Radiance includes a unique family of science-based, natural formulas including a sunscreen, "stem cell based" skin serum, internal beauty cleanse, and even the first skin cell DNA rejuvenation cream, based on Nobel Prize winning, telomere technology. Dr. Sears' commitment to beauty without chemicals keeps him on the cutting edge of anti-aging cosmetic science and skin care technology. His journeys to the most remote regions on earth to find native secrets enable him to create one-of-a-kind formulas for his Pure Radiance brand that you cannot get anywhere else. | Most skincare companies stopped short, relying heavily on just the apple extract's benefits alone to wow their customers. They neglected to tap into the real newsworthy breakthrough here when it comes to skincare and health. My name is Al Sears, MD. As one of the first doctors ever to be board certified in anti-aging medicine and a certified nutritionist, I specialize in developing my own natural beauty formulas to help my patients avoid the synthetic, toxic chemicals used in today's unnatural products. When I observed the skin damage chemically toxic beauty products and sunscreens inflicted on my patients, I recognized the need for an effective, wholesome and organic line of products that could maintain natural beauty without chemicals. I developed my Pure Radiance brand. In my natural formulas, I apply advanced anti-aging science with little known native beauty secrets to develop breakthrough beauty formulas. As someone who has a long history of looking beyond the latest fad, I knew there was something more. So I created a breakthrough anti-aging serum, Renew SCII, that takes full advantage of... A Natural Skin Care Revolution See, while this rare apple's ability to heal itself is extraordinary, the apple really isn't the star of this show. The real breakthrough is that scientists have figured out how to transfer the plant's knowledge to your skin. And Renew SCII taps into the wisdom of not just one but two amazing plants using this breakthrough extraction process... But there's more... Using the same extraction technique, Renew SCII transfers to your skin a hardy alpine daisy's defensive know-how. This tiny purple flower- called the globe daisy - blooms despite the extreme weather it endures perched on the side of the Alps.6 - Renew SCII shows your skin how to ward off the ravages of the environment like heat, pollution, wind and sun. So your skin looks radiant and fresh instead of weatherbeaten and - well - old.
This combination gives your skin the power to glow no matter your age or the environment you live in. - It is everything your aging skin craves to make it radiant and beautiful.
Together These Two Extracts Allow Your Skin To Radiate Nothing in skincare promises to bring your skin this close to the glory days of childhood - naturally and safely. You're probably already imagining what it would be like to see wrinkles start to fade as your skin becomes more vibrant and elastic, stretching taut across your face... But I'm sure you're also a little skeptical - the world of skincare is full of promises. And too many times these promises fall flat when you look in the mirror and see the same skin, the same lines, the same blemishes and dullness. So let's step back a moment... Let me explain how your skin works... and why these extractions wake up your skin's ability to keep itself young and beautiful unlike any other skin care ingredients... For The First Time, We Know How Skin Regenerates Until recently, scientists have not been able to agree about how the skin works. But then in June, 2013 Dr. Xinshan Li and a team of researchers at Sheffield University in England changed that. They showed incontrovertibly how your skin renews itself.7 See, battered by the environment, the cells at the surface of your skin are constantly dividing to replace themselves. However, there's only so many times each of these surface cells can divide before they give out. That's where a special group of cells hidden in the deeper layers of your skin comes in... Unlike the cells near the surface, these hidden cells don't divide much at all. They mostly "sleep". They only "wake up" and start dividing if your skin suffers a serious wound. Or to replenish the stock of quickly dividing skin cells near the surface. Then these special cells- called stem cells - rouse themselves. And start a whole new line of skin cells. If you didn't have the stem cells deep inside your skin, it wouldn't take long for your skin to fall apart and die. But thankfully, because you have these stem cells, your skin can keep bringing new life to the surface. Your skin can consistently recharge your skin's outer layers with new cell lines.8 The problem is over time, this population of skin stem cells dwindles away.9 That's why as we get older our skin doesn't heal as quickly. That's why you start to see more wrinkles... more blemishes... more bags and sags. If you could only keep the numbers of these cells up, you could keep your skin not just young "looking" but biologically young. But unfortunately, no one could figure out how to maintain their numbers better or replenish them. That is until now... The Secret Language Of Cells You and I both know we can't talk to our stem cells and get them to step it up a notch. But plants can. More specifically, plant stem cells can. It turns out our cells and plant cells speak basically the same language. They speak a language made up of signal molecules. Remember that rare Swiss apple that seemed to stay forever young? And that daisy that bloomed beautifully despite the roughest alpine weather? The cells from those plants have their own "language" to signal what they do. It's actually pretty simple. They cut the apple. And just as the apple starts to regrow the new skin, they take those cells and grow them into a larger culture. Essentially, they've captured the cells at the moment they are spreading the word to rebuild and renew. Out of this culture they get not only the regenerative cells, but also the signal molecules that tell the cells to renew.10 Of course all this sounds good... but does this really work? Scientists Demonstrate Amazing Results With New Plant Extracts Well here's the proof of how good this is... Researchers mixed some of the apple extract with a culture of human stem cells taken from an umbilical cord. The apple extract just about doubled the number of stem cells
in the culture!11 But researchers didn't stop there. They wanted to see what happens when the stem cells are being attacked... what would happen if they used UV light to damage the stem cells... would the apple extract make a difference? When exposed to UV light, 50% of the stem cells died. But when they added the apple extract, a tiny number - less than 10% - died. Even with damaging UV light, almost twice as many stem cells survived
thanks to the apple extract!12 The amazing results kept coming... the apple extract seemed to turn on genes that prevented stem cell death...protect cells against free radical destruction... and even repaired their DNA! And when 20 volunteers used the extract on their skin, the results were indisputable... 100% of the volunteers saw their wrinkles noticeably smoothed away
after just 28 days!13 I was very impressed by one Swiss clinical study. They recruited twenty women aged 37 to 64, and had them use a skin cream made from the Swiss apple for 28 days. In less than a month, every one of the women saw the depth of their wrinkles decrease by 15%. They even did 3-D imaging on the surface of the skin. This measured how much tighter and less visible the wrinkles had become. On the left, you'll notice that at the start of the study, the dark blues and greens indicate deep wrinkles and well-defined crow's feet. On the right, taken after the study, the reds and greens show that wrinkles are much shallower and the crow's feet are very diminished. The researchers also took photos of the volunteers before and after the study. Before the study, on the left, this volunteer had fine lines and crow's feet. After the study, on the right, the wrinkles and crow's feet are nearly gone... And that happened in less than a month! This cream, based on the apple extract, could make an impressive skin reviving formula all by itself! Researchers saw equally stunning results with the extract from the alpine flower...  | | The alpine flower extract more than doubled the number of human stem cells in the test cultures...14 | | This same extract: | | | Increased the number of skin cells in test cultures;15 | | | Stimulated the production of a protein (sirtuin-1) essential for skin longevity;16,17 and | | | Sped up skin's production of the super antioxidant SOD that protects against damage and hypersensitivity.18,19,20 | When volunteers used this on their skin, they saw more beautiful, luminous skin. Less redness and blemishes. More smooth, radiant beauty.21 In fact even smokers saw significant changes in their skin thanks to this extract.22 As one researcher explained, this mountain flower extract is like a self-defense class for your skin cells!23 It tells your cells how to step up their self-protection. No other ingredient can do this for your skin. Imagine what your skin would look like if you could double the amount of regenerative stem cells you had... Imagine if you could help your stem cells resist UV or free radical damage... Just with these two ingredients alone - two ingredients that complement each other so beautifully - you can... Transform Your Skin By Reminding It
How To Be Young And Supple With these two extracts alone you'd love what you'd see in the mirror... But I'm not one to give you an incomplete formulation. That's why I included some additional ingredients that will complement the work of these two special plant extracts... Renew SCII gives your skin a complete formula to... | | Fight Off Damaging Free Radicals | Free radicals are perhaps one of the biggest threats to your skin's health, breaking down the molecules that hold your skin together. - Renew SCII's Japanese Green Tea extract, Pantothenic acid (vitamin B5), vitamin C and L-Carnosine support your skin's endless battle against free radicals.
| | Replenish Your Skin's Natural Healthy Ecology | Instead of using harsh preservatives and antibacterial chemicals like some skincare products, Renew SCII nourishes a healthy skin ecology with yogurt and fermented radish extract. These two skin-ecology supporting ingredients help keep your skin tone even, rebalance your skin's natural pH and moisture.24,25 And without moisture, good nutrition and probiotics can't do their job. That's why Renew SCII also helps your skin... | | Hold On To Every Drop Of Water, Just Like A Baby's Skin | Your skin's most precious nutrient is water. - Renew SCII helps your skin hold moisture in by nourishing its outer layers with rich Moroccan argan nut oil and a special mixture of skin-healthy oils called ceramides.
- Renew SCII gives your skin more hyaluronic acid (HA). HA, found in high concentrations in a baby's skin, forms a special water-holding matrix.26 So your skin can hold onto every drop of moisture you bring in.
| | Experience An Instant "Face Lift" | - Extracts from yeast and DMAE help fuel skin cells making the appearance look firm...
- And a special microalgae extract combined with special sugars gives you almost instant results. Within minutes of application you'll feel your skin tighten up.27
You'll redefine your face with your cheekbones and beautiful brows - not with lines and bags. And unlike other quick fixes like Botox, these skin tighteners are healthy and safe. In fact your whole experience with Renew SCII will be enjoyable... Renew SCII Feels Good
On Your Skin! When you smooth Renew SCII on, your skin will feel clean and fresh. Never greasy or oily. No irritation like those Retinol-infused products... no skin dandruff from too much exfoliation... no redness... no dryness. Your skin will drink it up, almost sighing with delight... Sensitive skin... oily skin... delicate older skin... it doesn't matter what your skin type, you'll enjoy how it feels. The beautiful thing about the Renew SCII approach is that it works with your skin, nourishing it and guiding it. Not manhandling it like so many rough anti-aging lotions do. Renew SCII gives your skin a gentle, complete and effective formula for beating back the claws of time and the savage attacks of the environment. It's got everything your skin needs to rediscover its youth... and revel in it. So now let me ask you an important question: You'll NEVER Pay Saks Fifth Avenue Prices! Why spend $355 for the famous Swiss apple beauty secret when it has all those missing ingredients in the formula? I designed a more complete, more effective formula for LESS than HALF the cost of the Saks Fifth Avenue version. For the cost of a night out on the town, you'll get the celebrity-endorsed makeover of a lifetime... and more! Thousands of women have already paid well-over a hundred dollars a bottle for this amazing, stem-cell anti-aging formula... But I have made a special deal with the manufacturer so that I don't have to charge the usual $149. per bottle. Just so you can try this amazing stem-cell formula and experience the skin changing results for yourself, I am going to reduce the price down to $99 per bottle. See For Yourself How Renew SCII Recharges and Revitalizes Your Skin Completely RISK FREE You know not everyone's skin is the same. So you may be thinking, "What if I try this, and once again I'm disappointed?" That's why - unlike so many companies - I offer a full no questions asked, no time limit guarantee. I know how well Renew SCII works. I know how a beautiful complexion changes everything in how you present yourself and how others react to you. And I'd hate for you to miss out trying it for yourself over money. I'm happy to take ALL the risk. My Full Satisfaction Guarantee: No Questions, No Time Limit I promise you Renew SCII will: | | Use the breakthrough "signal molecule" technology to transform the way your skin behaves. You will see the appearance of fine lines and wrinkles smoothed away and your skin tone become soft and even. | | | Nourish your skin with natural and potent anti-aging ingredients | | | Make you feel 10 years younger - with the confidence and joy that comes with it | If it doesn't do this to your satisfaction, you can send me back the empty bottle, or bottles, at any time and get a full refund of your purchase price minus shipping and handling. I'm that confident that you're going to love what you see happening to your skin once you try it. Accept My Best, Limited-Time Offer and SAVE Even MORE! If you've read this far, you're probably as excited as I am about this development in anti-aging skincare. I have just completed a breakthrough special report that is a complete game-changer in anti-aging beauty science. "Unlocking The Beauty Code: The Genetic Secret To Staying Younger Longer" It is so important to me that you get this ground-breaking special report, I am going to give it to you FREE as part of my BEST one-time only offer. When you buy 2 bottles of Renew SCII for only $99.00. I'm going to include the special report as a Free Bonus. This is an over $300 value for only $99. PLUS: I'll pay for your shipping. All of my special deal offer come with the same 100% satisfaction, no time limit guarantee. As you can see now, this is an offer too good to pass up. With my 100% satisfaction guarantee and these special discounts, you now have no reason not to see how Renew SCII can transform your skin. Bring your skin back to its youthful glory days ... enjoy that delicious feeling of watching old friends do a double-take when they see you ... Enjoy the confidence that comes with Renew SCII... To Living A Beautiful Life, 
Al Sears, MD Order your complete beauty package right here:  Yes, Dr. Sears! I want to transform my skin with Renew SCII.
| BEST DEAL! Save $198 Order my BEST DEAL now and get 2 bottles of Renew SCII for only $99. with FREE shipping and handling. PLUS You'll also receive my just-released e-Report "Unlocking The Beauty Code: The Genetic Secret To Staying Younger Longer". 
| | Trial Offer - Save $50 You'll receive 1 bottle of Renew SCII for just $149 $99 +FREE shipping and handling. 
| | 
Here's what industry experts are saying about Dr. Sears: "Dr. Sears blows away the conventional medical wisdom…"
-Ronald Klatz, MD, DO Founder and President, American Academy of Anti-Aging Medicine
"Dr. Sears has distinguished himself as a leader in the area of Anti-Aging Medicine and recently in cell and telomere biology…"
-Frederic J. Vagnini, MD, FACS; Medical Director of the Heart, Diabetes and Weight Loss Centers of NY "Dr. Sears masterfully explains how we can flip the switches that allow access to the store of human vitality that resides within each one of us. We understood how to do this when we were young and now Dr. Sears gives us the evidence-based means to tap into our potency, strength, and stamina with intention."
-Paul L. Hester, MD, MBA "Dr. Al Sears really gets it. What a refreshing breath of fresh air…"
-Jonny Bowden, author, Living the Low Carb Life: From Atkins to the Zone Choosing the Diet That's Right for You 
1 A Swiss Apple A Day Keeps Wrinkles Away. Swiss Broadcasting Service.
2 ibid
3 Santisi, E.The Super Apple.Vogue. November 2009.
4 ibid
5 Hardy, L. Could The Extract Of A RARE Swiss Apple Extract Really Get Rid Of Your Wrinkles.UK Daily Mail.November 2009.
6 GlobulariaCordifolia.Royal Horticultural Society.
7 Virtual Skin Model Shows Secrets Of Aging.
8 X. Li et al. Skin Stem Cell Hypotheses and Long Term Clone Survival - Explored Using Agent-based ModellingScientific Reports 3, Article number: 1904 doi:10.1038/srep01904
9 sheffield.ac.uk/news/nr/virtual-model-skin-aging-sheffield-university-1.282738
10 Phyto Cell Tech Malusdomestica data sheet
11 PhytoCell Tech MalusDomestica data sheet.
12 ibid
13 ibid
14 Resistem data sheet
15 ibid
16 ibid
17 Moreau, Metal.Enhancing cell longevity for cosmetic application: a complementary approach.J Drugs Dermatol. 2007 Jun;6(6 Suppl):s14-9.
18 Niwa Y etal.Lipid peroxides and superoxide dismutase (SOD) induction in skin inflammatory diseases, and treatment with SOD preparations.Dermatologica. 1989;179Suppl 1:101-6.
19 Kim Y. Regulation of skin inflammation and angiogenesis by EC-SOD via HIF-1α and NF-κBpathways.FreeRadicBiol Med. 2011 Dec 1;51(11):1985-95. doi: 10.1016/j.freeradbiomed.2011.08.027. Epub 2011 Aug 30.
20 Resistem data sheet
21 Resistem data sheet
22 Resistem data sheet
23 Sederma launches Resistem - a natural ingredient with anti-aging benefits. Special Chem. 2011. Viewed 8/1/13 at
24 Leuconostoc data sheet
25 Yogurtene Balance. Adina Cosmetic Ingredients.
26 Ghersetich I etal.Hyaluronic acid in cutaneous intrinsic aging.Int J Dermatol. 1994 Feb;33(2):119-22.
27 Pepha-Tight data sheet | * These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease. | Pure Radiance, Inc. | 11905 Southern Blvd. | Royal Palm Beach, FL 33411 | 
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